Sensitivity in SEC-MALS mode: 0.4 µg BSA in PBS or comparable polystyrene in toluene   * Range of molar mass: 200 Da to 10 MDa (may vary with molecular composition, size or solvent)   * Range of rms radius Rg: 10 nm to 50 nm (up to 150 nm with specific shape models)   * Optional integrated modules: WyattQELS™ dynamic light scattering detector for particle sizes from 0.3 nm to 40 nm (Rh), and the COMET™ ultrasonic flow cell cleaner   * ASTRA® software provides a comprehensive set of analyses for macromolecules and nanoparticles    

The TREOS operates in combination with the Optilab® T-rEX™ or 3rd-party refractive index detector. In addition to chromatography mode, the TREOS may be used in conjunction with the Calypso? II composition-gradient system in order to analyze macromolecular/biomolecular interactions without labeling or immobilization, or in batch mode (off-line) for average solution molar mass and size using syringe injection, microcuvettes or scintillation vials.