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New Brunswick Scientific - CelliGen BLU

Manufactured by  New Brunswick Scientific
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Single-Use, Stirred-Tank Bioreactor

New Brunswick’s new CelliGen BLU cell culture bioreactor combines single-use technology with the trusted performance and true scalability of a traditional stirred-tank design. CelliGen BLU has been engineered for high-density animal cell culture in research or production, using interchangeable, single-use, stirred-tank vessels in 5.0 and 14.0 L total volume capacities. A compact controller enables advanced process management for research or cGMP manufacturing.
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Features of CelliGen BLU
  • The single-use vessel eliminates autoclaving and cleaning, provides rapid turnaround between runs, reduces risk of contamination, reduces validation requirements and minimizes initial startup costs.
  • Stirred-tank design provides proven performance and scalability.
  • The integrated control station enables advanced gas management and process control.
  • Unique pH and DO technology makes probe insertion totally noninvasive, eliminating contamination risk and making probe autoclaving unnecessary.
General Specifications
Depth 24 in Control Station & Vessel Including Touchscreen
Height34 in Control Station & Vessel Including Touchscreen
Width 25 in Control Station & Vessel Including Touchscreen
Power Requirements 100 - 120 VAC 50/60 Hz, Single phase, 15 Amps
Additional Specifications

[u]Controller[/u]
Control Station:
Controls up to 32 control loops; stores 10 recipes and 8 process variables for trend graphing. Includes an industrial touchscreen monitor/user interface, 3 built-in pumps and connectors for all utilities and communications signals
Touchscreen Interface/Display: 15-inch (38.1 cm) color industrial monitor with adjustable-angle swivel

[u]Temperature[/u]
Indication: Digital display in 0.1°C increments
Range: From 5°C above ambient temperature to 40°C
Control: P&I for heating using a Heat Blanket (cooling via ambient environment)
Sensor: Platinum RTD probe

[u]Agitation[/u]
Drive: Permanent magnet motor with high torque input
Indication: Digital display in 1 rpm increments
Range: 25 - 200 rpm
Control: PI-controlled
Impellers: Pitched blade (upflow or downflow selectable via touchscreen)

[u]Exhaust[/u]
Filter: 0.2 Μm disposable filter
Tube: Heat blanketed

[u]Aeration[/u]
3- or 4-Gas System:
Up to 4 gases, including air, N2, CO2 and O2, delivered to sparge and overlay
Flow Control: Automatic or manual options
Sparge:
1, 3 or 4 TMFCs (0.002 - 0.1 SLPM) – Automatic option
1 Rotameter (0.001 - 0.1 SLPM) – Manual option
Optional Overlay:
1 TMFC (0.1 - 3.0 SLPM) – Automatic option
1 Rotameter (0.1 - 3.3 SLPM) – Manual option
Sparge Element: Porous microsparger (6 - 12 Μm)
Inlet Filters: 0.2 Μm disposable filter

[u]pH[/u]
Indication: Digital display in 0.01 pH increments
Range: 6 - 8 pH
Control: P&I
Probe: Noninvasive optical pH probe. Single-use fluorescence sensor is included with each vessel

[u]DO[/u]
Indication: Digital display in 0.1% increments
Range: 0 - 200%
Control: P&I
Probe: Noninvasive, reusable polarographic probe

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