Discussion Category:  LC-MS Systems

Loss of intensity and drifting of resolution values

Hello!

I'm a operator of AB Sciex QTrap4500. I have a problem with drifting of resolution values (width on PPG masses were about 0.3) and a loss of intensity (on PPG the intensity is normal, but on the analyte it became lower than it was). What can be a reason of these problems?

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MayaAbizova
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